La glutamine is a conditionally essential amino acid, la online sale of glutamine it is essential for food supplementation as although it is synthesized by the human body, in some conditions it requires adequate intake through the diet.
Constituting the most abundant amino acid in the human body, the need for glutamine it can significantly increase during stress, surgical trauma, burns, tumors or particularly intense physical exercise.
Glutamine is widely present both in products of animal origin, such as meat, fish, eggs and dairy products, and in plant products.
Glutamine supplement
In light of its biological role, theglutamine supplement it is successfully used in both clinical and sports fields.
As for the functions of major sporting interest, glutamine also seems to intervene:
In increasing the volume of muscle cells, favoring the entry of water into the cells, fundamental amino acids and other substances. This activity, according to some researchers, would stimulate protein synthesis favoring themuscle mass gain.
Glutamine in training
In fact, there is a relationship between the permanent drop in plasma levels of gultamine and the appearance of overtraining symptoms (chronic fatigue, weight loss, loss of appetite, appearance of minor infections, nausea, depression, apathy, increased heart rate a rest and decrease in training heart rate).
According to some researchers, the administration of gultamine ed branched chain amino acids it would therefore be useful in periods of intense training to reduce the risks of overtraining.
In recovery after exertion: some studies show a role of glutamimine in favoring the increase of stocks of glycogen muscle during recovery, probably due to the increased entry of water into the cells (remember in this regard that water is essential in glycogenosynthesis, as for each gram of glycogen produced about 2,7 g binds to it of water).
In the secretion stimulus ofgrowth hormone; when taken in low blood sugar conditions, glutamine appears to stimulate secretion of GH. To optimize this action, glutamine should be taken before going to bed.
Glutamine is a non-essential amino acid and represents 2/3 of the amino acids present in the muscles. Most of the glutamine in the bloodstream is produced by muscles and some organs, such as the liver.
Many of the other amino acids, especially BCAAs, act as precursors.
Studies have shown that increased muscle hydration can affect muscle growth; the greater the hydration, the greater the rate of protein synthesis (also for this reason it is recommended to drink a lot of water). Logically, the decrease in cell volume is strongly catabolic. Glutamine is able to increase muscle hydration.
The depletion of this amino acid follows a strange course consisting of 2 phases:
The first that decreases is glutamine in the blood and occurs almost at the start of training. To compensate for the deficit, the muscles begin to synthesize new glutamine from other amino acids, such as BCAAs and this inevitably leads to the exhaustion of the latter. Eventually, the newly synthesized glutamine passes into the bloodstream, causing muscle deficiency. All this brings our organism towards a state of catabolism, due to a decrease in glutamine and amino acids which are used for resynthesis.
A glutamine deficiency, as previously mentioned, leads to a reduction in protein synthesis which is accentuated in the hours following a workout; since night fasting also causes a loss of glutamine, the two processes combine and increase catabolism. It goes without saying that if you train when your glutamine stores are still low, you are going to overtrain.
Consumption of l glutamine is significant during training because:
1. Intense training causes an increase in cortisol, which is a substance that induces its waste the most, degrading it.
2. Exercise increases the body's consumption of carbohydrates, so both insulin and blood sugar levels are very likely to drop. This induces the use of other substances, apart from carbohydrates, as an energy source; therefore, both the liver and the kidneys take up amino acids, mainly alanine and glutamine, for energy.
3. Another function of glutamine is to maintain ACID-BASE balance.
As we train with weights, the muscles produce lactic acid, which passes into the bloodstream and acidifies it. The increase in lactic acid induces a drop in pH (pH is the measurement scale for the concentration of hydrogen ions. A pH below 7 indicates an acidic environment, a pH above 7 indicates a basic environment) .
In this situation, the renal consumption of glutamine can be enormous, which indirectly raises the percentage of bicarbonate. After the newly synthesized bicarbonate has reached the blood, it serves as a buffer by binding to the acid part of the blood to make it at neutral pH and restore the acid-base balance.
4. Glutamine is an excellent fuel for the cells of the immune system.
5. Glutaminic acid produced in the brain from glutamine together with glucose is the primary fuel of brain cells and also, when combined with ammonia, detoxifies the brain.
INTAKE OF L-GLUTAMINE
Glutamine alone is unstable in the presence of water, heat and pH changes (this should make us think about those liquid supplements that claim to contain glutamine).
The most serious problem is that once ingested, a large part of it fails to pass into the blood, ie about 60 - 80% is absorbed by the intestine; the remainder is too little to meet the needs of our muscles.
Its combination with ALANINE + GLYCINE + BCAA is excellent. The first two make glutamine much more stable, while BCAAs are its precursors.
The peptide one is preferred to simple glutamine because it is clearly superior.
The glutamine in peptide bond means that it is linked to another amino acid which makes the compound much more stable.
Studies have shown that this peptide form makes glutamine 10 times higher than the simple form.
It is also recommended because:
1. It gets absorbed faster
2. It is not used and broken down by the gut and liver as quickly as free glutamine.
GLUTAMINE DOSES
5g are taken. before a workout and 5 / 10g after the workout for faster recovery and to reduce cortisol levels.
