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In this category you will find the best Vitamin D supplements in its active form cholecalciferol (D3) with and without K2 and Calcium. Unlike other water and fat-soluble vitamins, this micronutrient is a real modulator of the immune system and hormonal structure.

The integration with D3 is in fact indicated in cases of specific deficiencies (its levels can be measured through the serological test VITAMIN D-25OH), and is particularly useful for its action immuno-modulating, i.e. the ability to regulate immune function where there are malfunctions and / or autoimmune phenomena.

The benefits deriving from the integration of Vitamin D

Being a real hormone, vitamin D3 plays multiple roles ranging from support structural skeletal, immune, hormonal e anti-inflammatory. In particular, cholecalciferol acts on the body by improving the following aspects:

  • fixation of calcium in bone tissue, a very important peculiarity in both children and the elderly subject to osteoporosis and other types of structural joint wear;

  • immunomodulation, i.e. the ability to regulate normal immune function without overstimulating it (immunostimulating effect). This is a very interesting feature allowed by the innate ability to fight pathogens and by the complex relationship between the microbiota and the modulation of the immune system itself;

  • hormonal support, again in terms of regulation between the secretion of androgenic and estrogenic hormones. Again, taking a vitamin D3 supplement can delay the onset of menopause and andropause.

Why take Vitamin D3 and K2 together

Vitamin D is a fat-soluble vitamin micronutrient, that is, it needs to be dissolved in dietary fats to be properly assimilated. This high affinity for lipid molecules, albeit rarely, could cause storage toxicity in the body when taken in excess. In practice, an overdose of cholecalciferol would initiate its deposit in adipose tissues and organs such as brain, liver, visceral fat and others, causing severe toxicity for the organism. In this context, vitamin K2 fulfills two fundamental roles: it carries vitamin D3 avoiding its organic accumulation and acts by rebalancing the calcium levels and improving its fixation in the tissue.

Synergies with other supplements and recommended dosage

Being mainly an immuno-modulating agent and at the same time a support for bone density, its intake can be associated with other highly specific supplements such as:

  • Vitamin C: , Lactoferrin, B vitamins and other immuno-stimulating plant extracts, in order to improve the body's defenses;
  • K2, Calcio and others supplements for joint structures, in order to optimize the strength and elasticity of bones and connective tissues (tendons, ligaments and cartilages).

The maximum dose indicated by the Ministry of Health corresponds to 2000UI per day. However, the extensive MuscleNutrition.com catalog offers products containing dosages ranging from 400UI and up to 10.000UI. It is therefore advisable to consult your doctor before taking any dietary supplement, especially if it contains fat-soluble vitamins like this one.

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